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Search Type: Product Name, Cat No., CAS No., Chemical Name
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Angiogenesis
BTK inhibitor
FLT3 inhibitor
FGFR inhibitor
Bcr-Abl inhibitor
HIF inhibitor
Syk inhibitor
VEGFR inhibitor
Src inhibitor
ALK inhibitor
EGFR inhibitor
HIF modulator
FAK inhibitor
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Apoptosis
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Serine/threonin kinase inhibitor
PERK inhibitor
Mdm2 inhibitor
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ASK inhibitor
p53 inhibitor
Survivin inhibitor
Autophagy
Autophagy inhibitor
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Cell Cycle
CDK inhibitor
Aurora Kinase inhibitor
Rho inhibitor
Chk inhibitor
PLK inhibitor
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ROCK inhibitor
DYRK inhibitor
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Wee1 inhibitor
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APC inhibitor
Cytoskeletal Signaling
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Epigenetics
Histone Methyltransferase inhibitor
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STAT inhibitor
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kit
kit
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Transferase inhibitor
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Dehydrogenase inhibitor
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Proteases
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Trk receptor inhibitor
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Stemness kinase inhibitor
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CFTR inhibitor
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P-gp inhibitor
CRM1 inhibitor
Potassium Channel antagonist
TRPV inhibitor
CFTR activator
OCT activator
ATPase activator
Sodium Channel antagonist
CFTR modulator
P-gp modulator
Ubiquitin
E3 Ligase inhibitor
DUB inhibitor
p97 inhibitor
E2 conjugating inhibitor
E1 Activating inhibitor
Recommends
more>>
Cat#
Goods Name
Description
CC7285
PYR-41
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme
E1
, with no activity at E2.
CC3022
U-104
U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and
CA XII
with
K
i
of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II.
CC8170
GW9508
GW9508 is a potent and selective agonist for
FFA1 (GPR40)
with
pEC50
of 7.32, 100-fold selective against GPR120, stimulates insulin secretion in a glucose-sensitive manner.
CC1228
ZSTK474
ZSTK474 inhibits class I
PI3K
isoforms with
IC50
of 37 nM in a cell-free assay, mostly PI3Kδ. Phase1/2.
CC7577
CGP 57380
CGP 57380 is a potent
MNK1
inhibitor with
IC50
of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.
CC4675
Citric acid trilithium salt tetrahydrate
Citric acid trilithium salt tetrahydrate is a pharmaceutical and construction material. It is commonly used in HPLC gradient elution for quantification of amino acids.
CC7299
LGK-974
LGK-974 is a potent and specific
PORCN
inhibitor, and inhibits Wnt signaling with
IC50
of 0.4 nM in TM3 cells. Phase 1.
CC8096
NSC12
NSC12 is an orally available pan-FGF trap able to inhibit
FGF2/FGFR
interaction and endowed with promising antitumor activity.
CC7843
GSK269962 HCl
GSK269962 is a selective
ROCK(Rho-associated protein kinase)
inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
CC4834
Povidone iodine
Povidone iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It is used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol.
CC1166
Nintedanib (BIBF 1120)
Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for
VEGFR1/2/3
,
FGFR1/2/3
and
PDGFRα/β
with
IC50
of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.
CC4706
Azelaic acid
Azelaic acid is an organic compound produced by the ozonolysis of oleic acid and possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity.
CC7525
4EGI-1
4EGI-1 is a competitive
eIF4E/eIF4G
interaction inhibitor by binding to eIF4E with
K
D
of 25 μM.
CC4375
Azaperone
Azaperone crosses the blood-brain barrier and binds to both DI and D2 receptors, being an antagonist of
Dopamine receptors
with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.
CC2097
Enalapril Maleate
Enalapril Maleate is an
angiotensin-converting enzyme (ACE)
inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.
CC4178
Probenecid
Probenecid is a classical competitive inhibitor of
organic anion transport
, which is also a
TRPV2
agonist and an inhibitor of
TAS2R16
.
CC4311
Chlorzoxazone
Chlorzoxazone is a muscle-relaxing drug,and a probe for human liver cytochrome P-450IIE1.
CC8637
SRT3025 HCl
SRT3025 is an orally available small molecule activator of the
SIRT1
enzyme.
CC4206
Valganciclovir HCl
Valganciclovir HCl is a prodrug for ganciclovir with antiviral activity used to treat cytomegalovirus infections.
CC2636
Loperamide HCl
Loperamide HCl is a selective
μ-opioid receptor
agonist opioid with
K
i
of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or
CC9327
ACY-738
ACY-738 demonstrates inhibitory activity against recombinant HDAC6 with IC50 values of 1.7 nM, with respective average selectivity over class I HDACs being 100-fold.
CC4215
Sodium Nitroprusside Dihydrate
Sodium Nitroprusside Dihydrate is a potent vasodilator working through releasing NO spontaneously in blood.
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