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Description:
Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases.
Chemical Information:
Molecular Weight (MW) 453.51 Formula
C15H23N5O2S.C4H4O4
CAS No. 1640292-55-2 Solubility (25°C) * DMSO 90 mg/mL (198.45 mM) Water 18 mg/mL (39.69 mM) Alcohol 90 mg/mL (198.45 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.2050 mL 11.0251 mL 22.0502 mL 5 mM 0.4410 mL 2.2050 mL 4.4100 mL 10 mM 0.2205 mL 1.1025 mL 2.2050 mL 50 mM 0.0441 mL 0.2205 mL 0.4410 mL
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