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VU 0361737

VU 0361737

Catalog Number: CC3048 Rank: comment rank 5

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$ 259.00
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Description:

VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.

Chemical Information:

Molecular Weight (MW) 262.69
Formula

 

C13H11ClN2O2

 

CAS No. 1161205-04-4
Solubility (25°C) * DMSO 53 mg/mL (201.75 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.8068 mL 19.0338 mL 38.0677 mL
5 mM 0.7614 mL 3.8068 mL 7.6135 mL
10 mM 0.3807 mL 1.9034 mL 3.8068 mL
50 mM 0.0761 mL 0.3807 mL 0.7614 mL


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