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Loperamide HCl

Loperamide HCl

Catalog Number: CC2636 Rank: comment rank 5

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Description:

Loperamide HCl is a selective μ-opioid receptor agonist opioid with Ki of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.

Chemical Information:

Molecular Weight (MW) 513.5
Formula

 

C29H33ClN2O2.HCl

 

CAS No. 34552-83-5
Solubility (25°C) * DMSO 22 mg/mL (42.84 mM)
Water Insoluble
Alcohol 4 mg/mL (7.78 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9474 mL 9.7371 mL 19.4742 mL
5 mM 0.3895 mL 1.9474 mL 3.8948 mL
10 mM 0.1947 mL 0.9737 mL 1.9474 mL
50 mM 0.0389 mL 0.1947 mL 0.3895 mL


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