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Search Type: Product Name, Cat No., CAS No., Chemical Name
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Angiogenesis
BTK inhibitor
FLT3 inhibitor
FGFR inhibitor
Bcr-Abl inhibitor
HIF inhibitor
Syk inhibitor
VEGFR inhibitor
Src inhibitor
ALK inhibitor
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Autophagy
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Cell Cycle
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Aurora Kinase inhibitor
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Epigenetics
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kit
kit
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Transferase inhibitor
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Stemness kinase inhibitor
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P-gp inhibitor
CRM1 inhibitor
Potassium Channel antagonist
TRPV inhibitor
CFTR activator
OCT activator
ATPase activator
Sodium Channel antagonist
CFTR modulator
P-gp modulator
Ubiquitin
E3 Ligase inhibitor
DUB inhibitor
p97 inhibitor
E2 conjugating inhibitor
E1 Activating inhibitor
Recommends
more>>
Cat#
Goods Name
Description
CC8170
GW9508
GW9508 is a potent and selective agonist for
FFA1 (GPR40)
with
pEC50
of 7.32, 100-fold selective against GPR120, stimulates insulin secretion in a glucose-sensitive manner.
CC7349
1-Azakenpaullone
1-Azakenpaullone is a potent and selective
GSK-3β
inhibitor with
IC50
of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.
CC2097
Enalapril Maleate
Enalapril Maleate is an
angiotensin-converting enzyme (ACE)
inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.
CC3189
Vildagliptin (LAF-237)
Vildagliptin (LAF-237) inhibits
DPP−4
with
IC50
of 2.3 nM.
CC2720
Cloxacillin Sodium
Cloxacillin Sodium is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin.
CC7311
Batimastat (BB-94)
Batimastat (BB-94) is a potent, broad spectrum
matrix metalloprotease (MMP)
inhibitor for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3 with
IC50
of 3 nM, 4 nM, 4 nM, 6 nM and 20 nM, respectively. Also inhibits the activitity of other metalloprotease
CC9327
ACY-738
ACY-738 demonstrates inhibitory activity against recombinant HDAC6 with IC50 values of 1.7 nM, with respective average selectivity over class I HDACs being 100-fold.
CC3193
Bepotastine Besilate
Bepotastine is a non-sedating, selective antagonist of
histamine 1 (H1)
receptor with
pIC50
of 5.7.
CC4706
Azelaic acid
Azelaic acid is an organic compound produced by the ozonolysis of oleic acid and possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity.
CC2636
Loperamide HCl
Loperamide HCl is a selective
μ-opioid receptor
agonist opioid with
K
i
of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or
CC1957
Ranitidine Hydrochloride
Ranitidine is a
histamine H2-receptor
antagonist, used to treat stomach or intestinal ulcers.
CC8637
SRT3025 HCl
SRT3025 is an orally available small molecule activator of the
SIRT1
enzyme.
CC7285
PYR-41
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme
E1
, with no activity at E2.
CC7667
LY2857785
LY2857785 is a type I reversible and competitive ATP kinase inhibitor against
CDK9
(IC50=0.011 μM) and also inhibits other transcription kinases
CDK8
(IC50=0.016 μM) and
CDK7
(IC50=0.246 μM).
CC4675
Citric acid trilithium salt tetrahydrate
Citric acid trilithium salt tetrahydrate is a pharmaceutical and construction material. It is commonly used in HPLC gradient elution for quantification of amino acids.
CC8351
Oclacitinib maleate
Oclacitinib is a novel inhibitor of
JAK
family members with
IC50
ranging from 10 to 99 nM and JAK1-dependent cytokines with
IC50
ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases.
CC7205
Oprozomib (ONX 0912)
Oprozomib (ONX 0912) is an orally bioavailable inhibitor for CT-L activity of
20S proteasome
β5/LMP7 with
IC50
of 36 nM/82 nM. Phase 1/2.
CC7486
6H05
6H05 is a selective, and allosteric inhibitor of oncogenic
K-Ras(G12C)
.
CC1228
ZSTK474
ZSTK474 inhibits class I
PI3K
isoforms with
IC50
of 37 nM in a cell-free assay, mostly PI3Kδ. Phase1/2.
CC8430
STO-609
STO-609 is a specific inhibitor of the
Ca2+/Calmodulin-dependent protein kinase kinase(CaM-KK)
that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms, with Ki values of 80 and 15 ng/ml, respectively, and also inhibits their autoph
CC7160
EPZ005687
EPZ005687 is a potent and selective inhibitor of
EZH2
with
K
i
of 24 nM in a cell-free assay, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.
CC4206
Valganciclovir HCl
Valganciclovir HCl is a prodrug for ganciclovir with antiviral activity used to treat cytomegalovirus infections.
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