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Dalcetrapib (JTT-705, RO4607381)

Dalcetrapib (JTT-705, RO4607381)

Catalog Number: CC2928 Rank: comment rank 5

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Description:

Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM that increases the plasma HDL cholesterol. Phase 3.

Chemical Information:

Molecular Weight (MW) 389.59
Formula

 

C23H35NO2S

 

CAS No. 211513-37-0
Solubility (25°C) * DMSO 78 mg/mL (200.21 mM)
Water Insoluble
Alcohol 78 mg/mL (200.21 mM)


Biological Activity:

Targets
IC50
PLK1
2 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.5668 mL 12.8340 mL 25.6680 mL
5 mM 0.5134 mL 2.5668 mL 5.1336 mL
10 mM 0.2567 mL 1.2834 mL 2.5668 mL
50 mM 0.0513 mL 0.2567 mL 0.5134 mL


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