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Momelotinib (CYT387)

Momelotinib (CYT387)

Catalog Number: CC2375 Rank: comment rank 5

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Description:

Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. Phase 3.

Chemical Information:

Molecular Weight (MW) 414.46
Formula

 

C23H22N6O2

 

CAS No. 1056634-68-4
Solubility (25°C) * DMSO 74 mg/mL (178.54 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.4128 mL 12.0639 mL 24.1278 mL
5 mM 0.4826 mL 2.4128 mL 4.8256 mL
10 mM 0.2413 mL 1.2064 mL 2.4128 mL
50 mM 0.0483 mL 0.2413 mL 0.4826 mL


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