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MK-2206 2HCl

MK-2206 2HCl

Catalog Number: CC1234 Rank: comment rank 5

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Description:

MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. Phase 2.

Chemical Information:

Molecular Weight (MW) 480.39
Formula

 

C25H21N5O.2HCl

 

CAS No. 1032350-13-2
Solubility (25°C) * DMSO 14 mg/mL (29.14 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0816 mL 10.4082 mL 20.8164 mL
5 mM 0.4163 mL 2.0816 mL 4.1633 mL
10 mM 0.2082 mL 1.0408 mL 2.0816 mL
50 mM 0.0416 mL 0.2082 mL 0.4163 mL


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