Description：

Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Phase 3.

Chemical Information：

Molecular Weight (MW)		396.49
Formula		C21H28N6O2
CAS No.		779353-01-4
Solubility (25°C) *	DMSO	26 mg/mL warmed (65.57 mM)
	Water	Insoluble
	Alcohol	8 mg/mL warmed (20.17 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5221 mL	12.6107 mL	25.2213 mL
5 mM	0.5044 mL	2.5221 mL	5.0443 mL
10 mM	0.2522 mL	1.2611 mL	2.5221 mL
50 mM	0.0504 mL	0.2522 mL	0.5044 mL

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