Description：

AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.

Chemical Information：

Molecular Weight (MW)		660.52
Formula		C30H22F6N6O5
CAS No.		1256094-72-0
Solubility (25°C) *	DMSO	100 mg/mL (151.39 mM)
	Water	Insoluble
	Alcohol	100 mg/mL warmed (151.39 mM)

Biological Activity：

Targets IC50

HDAC10 HDAC1 HDAC4 HDAC11 HDAC2 0.46 nM 0.11 nM 0.64 nM 0.37 nM 0.33 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.5140 mL	7.5698 mL	15.1396 mL
5 mM	0.3028 mL	1.5140 mL	3.0279 mL
10 mM	0.1514 mL	0.7570 mL	1.5140 mL
50 mM	0.0303 mL	0.1514 mL	0.3028 mL

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