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Alendronate sodium trihydrate

Alendronate sodium trihydrate

Catalog Number: CC1780 Rank: comment rank 5

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Description:

Alendronate sodium trihydrate, a nitrogen-containing bisphosphonate, is a potent inhibitor of bone resorption used for the treatment and prevention of osteoporosis.

Chemical Information:

Molecular Weight (MW) 326.13
Formula

 

C4H13NO7P2.3H2O.Na

 

CAS No. 121268-17-5
Solubility (25°C) * DMSO Insoluble
Water 20 mg/mL warmed (61.32 mM)
Alcohol Insoluble


Biological Activity:

Targets
IC50
p110α p110β p110δ
0.5 μM 0.97 μM 0.57 μM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.0663 mL 15.3313 mL 30.6626 mL
5 mM 0.6133 mL 3.0663 mL 6.1325 mL
10 mM 0.3066 mL 1.5331 mL 3.0663 mL
50 mM 0.0613 mL 0.3066 mL 0.6133 mL


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