Search  
Your Position: Home > Protein Tyrosine Kinase > EGFR inhibitor > AEE788 (NVP-AEE788)
All Categories
AEE788 (NVP-AEE788)

AEE788 (NVP-AEE788)

Catalog Number: CC1642 Rank: comment rank 5

Size Price Qty
$ 118.00
$ 224.00
$ 399.00
$ 679.00
Total:
    
ChecmCatch Tel: 021-65878381 QQ Online
Email: kelvinyeng@hotmail.com    info@chemcatch.cn

Goods Info

Releate

Other

Description:

AEE788 (NVP-AEE788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCα and CDK1. Phase 1/2.

Chemical Information:

Molecular Weight (MW) 440.58
Formula

 

C27H32N6

 

CAS No. 497839-62-0
Solubility (25°C) * DMSO 88 mg/mL (199.73 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
EGFR EGFR
5.2 pM (Ki) 29 pM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.2697 mL 11.3487 mL 22.6974 mL
5 mM 0.4539 mL 2.2697 mL 4.5395 mL
10 mM 0.2270 mL 1.1349 mL 2.2697 mL
50 mM 0.0454 mL 0.2270 mL 0.4539 mL


Bought notes(bought amounts latest0)

No one bought this product
Total 0 records, divided into1 pages. First Prev Next Last
Chem Catch products are for research use only. Not for human use. We do not sell to patients. 沪ICP备16042327号-1