Description：

ADL5859 HCl is a δ-opioid receptor agonist with K_i of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel. Phase 2.

Chemical Information：

Molecular Weight (MW)		428.95
Formula		C24H28N2O3.HCl
CAS No.		850173-95-4
Solubility (25°C) *	DMSO	86 mg/mL (200.48 mM)
	Water	5 mg/mL (11.65 mM)
	Alcohol	1 mg/mL (2.33 mM)

Biological Activity：

Targets IC50

GSK-3α 34.3 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3313 mL	11.6564 mL	23.3127 mL
5 mM	0.4663 mL	2.3313 mL	4.6625 mL
10 mM	0.2331 mL	1.1656 mL	2.3313 mL
50 mM	0.0466 mL	0.2331 mL	0.4663 mL

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