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Entinostat (MS-275)

Entinostat (MS-275)

Catalog Number: CC1209 Rank: comment rank 5

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Description:

Entinostat (MS-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM in cell-free assays, compared with HDACs 4, 6, 8, and 10. Phase 3.

Chemical Information:

Molecular Weight (MW) 376.41
Formula

 

C21H20N4O3

 

CAS No. 209783-80-2
Solubility (25°C) * DMSO 75 mg/mL (199.25 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.6567 mL 13.2834 mL 26.5668 mL
5 mM 0.5313 mL 2.6567 mL 5.3134 mL
10 mM 0.2657 mL 1.3283 mL 2.6567 mL
50 mM 0.0531 mL 0.2657 mL 0.5313 mL


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