Description：

Eltrombopag, a member of the biarylhydrazone class, is a nonpeptide agonist of the thrombopoietin receptor (TpoR), used to treat chronic hepatitis C-associated thrombocytopenia and chronic immune (idiopathic) thrombocytopenia (ITP).

Chemical Information：

Molecular Weight (MW)		442.47
Formula		C25H22N4O4
CAS No.		496775-61-2
Solubility (25°C) *	DMSO	26 mg/mL warmed (58.76 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

histamine H1 10 nM/19 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2600 mL	11.3002 mL	22.6004 mL
5 mM	0.4520 mL	2.2600 mL	4.5201 mL
10 mM	0.2260 mL	1.1300 mL	2.2600 mL
50 mM	0.0452 mL	0.2260 mL	0.4520 mL

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