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EI1

EI1

Catalog Number: CC7767 Rank: comment rank 5

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Description:

EI1 is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.

Chemical Information:

Molecular Weight (MW) 390.48
Formula

 

C23H26N4O2

 

CAS No. 1418308-27-6
Solubility (25°C) * DMSO 42 mg/mL warmed (107.55 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
PDE5
5.2 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.5610 mL 12.8048 mL 25.6095 mL
5 mM 0.5122 mL 2.5610 mL 5.1219 mL
10 mM 0.2561 mL 1.2805 mL 2.5610 mL
50 mM 0.0512 mL 0.2561 mL 0.5122 mL


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