Description：

Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.

Chemical Information：

Molecular Weight (MW)		572.59
Formula		C21H21FN6O.2C3H6O3
CAS No.		852433-84-2
Solubility (25°C) *	DMSO	90 mg/mL (157.18 mM)
	Water	70 mg/mL (122.25 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7465 mL	8.7323 mL	17.4645 mL
5 mM	0.3493 mL	1.7465 mL	3.4929 mL
10 mM	0.1746 mL	0.8732 mL	1.7465 mL
50 mM	0.0349 mL	0.1746 mL	0.3493 mL

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