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Alcaftadine

Alcaftadine

Catalog Number: CC4781 Rank: comment rank 5

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$ 172.00
$ 347.00
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Description:

Alcaftadine is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.

Chemical Information:

Molecular Weight (MW) 307.39
Formula

 

C19H21N3O

 

CAS No. 147084-10-4
Solubility (25°C) * DMSO 28 mg/mL (91.08 mM)
Water Insoluble
Alcohol 61 mg/mL (198.44 mM)


Biological Activity:

Targets
IC50
Aurora A Aurora B
110 nM 130 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.2532 mL 16.2660 mL 32.5320 mL
5 mM 0.6506 mL 3.2532 mL 6.5064 mL
10 mM 0.3253 mL 1.6266 mL 3.2532 mL
50 mM 0.0651 mL 0.3253 mL 0.6506 mL


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