Description：

Darapladib (SB-480848) is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. Phase 3.

Chemical Information：

Molecular Weight (MW)		666.77
Formula		C36H38F4N4O2S
CAS No.		356057-34-6
Solubility (25°C) *	DMSO	100 mg/mL warmed (149.97 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (149.97 mM)

Biological Activity：

Targets IC50

PAR1 0.26 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.4998 mL	7.4988 mL	14.9977 mL
5 mM	0.3000 mL	1.4998 mL	2.9995 mL
10 mM	0.1500 mL	0.7499 mL	1.4998 mL
50 mM	0.0300 mL	0.1500 mL	0.3000 mL

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