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Cucurbitacin B

Cucurbitacin B

Catalog Number: CC8321 Rank: comment rank 5

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Description:

Cucurbitacin B, an oxygenated tetracyclic triterpenoid compound extracted from Cucurbitaceae plant species, is a long-term anticancer agent by disruption of microtubule polymerization.

Chemical Information:

Molecular Weight (MW) 558.70
Formula

 

C32H46O8

 

CAS No. 6199-67-3
Solubility (25°C) * DMSO 100 mg/mL (178.98 mM)
Water Insoluble
Alcohol 50 mg/mL warmed (89.49 mM)


Biological Activity:

Targets
IC50
IGF-1R Pyk2 FAK
0.14 μM 3.5 nM 5.5 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.7899 mL 8.9493 mL 17.8987 mL
5 mM 0.3580 mL 1.7899 mL 3.5797 mL
10 mM 0.1790 mL 0.8949 mL 1.7899 mL
50 mM 0.0358 mL 0.1790 mL 0.3580 mL


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