Description：

AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR.

Chemical Information：

Molecular Weight (MW)		315.75
Formula		C16H14ClN3O2
CAS No.		153436-53-4
Solubility (25°C) *	DMSO	25 mg/mL (79.17 mM)
	Water	Insoluble
	Alcohol	13 mg/mL (41.17 mM)

Biological Activity：

Targets IC50

IGF-1R 0.17 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1671 mL	15.8353 mL	31.6706 mL
5 mM	0.6334 mL	3.1671 mL	6.3341 mL
10 mM	0.3167 mL	1.5835 mL	3.1671 mL
50 mM	0.0633 mL	0.3167 mL	0.6334 mL

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