Description：

CPI-0610 is a potent and selective benzoisoxazoloazepine BET bromodomain inhibitor and currently undergoing human clinical trials for hematological malignancies.

Chemical Information：

Molecular Weight (MW)		365.81
Formula		C20H16ClN3O2
CAS No.		1380087-89-7
Solubility (25°C) *	DMSO	73 mg/mL (199.55 mM)
	Water	Insoluble
	Alcohol	12 mg/mL (32.8 mM)

Biological Activity：

Targets IC50

PI3Kα PI3Kβ 0.469 nM 3.72 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.7337 mL	13.6683 mL	27.3366 mL
5 mM	0.5467 mL	2.7337 mL	5.4673 mL
10 mM	0.2734 mL	1.3668 mL	2.7337 mL
50 mM	0.0547 mL	0.2734 mL	0.5467 mL

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