Description：

Citarinostat (ACY-241) is an orally available selective HDAC6 inhibitor with IC50 of 2.6 nM and 46 nM for HDAC6 and HDAC3, respectively. It has 13 to 18-fold selectivity towards HDAC6 in comparison to HDAC1-3.

Chemical Information：

Molecular Weight (MW)		467.95
Formula		C24H26ClN5O3
CAS No.		1316215-12-9
Solubility (25°C) *	DMSO	41 mg/mL (87.61 mM)
	Water	Insoluble
	Alcohol	93 mg/mL (198.73 mM)

Biological Activity：

Targets IC50

Mps1 ~35 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1370 mL	10.6849 mL	21.3698 mL
5 mM	0.4274 mL	2.1370 mL	4.2740 mL
10 mM	0.2137 mL	1.0685 mL	2.1370 mL
50 mM	0.0427 mL	0.2137 mL	0.4274 mL

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