Description：

Ceritinib (LDK378) is potent inhibitor against ALK with IC50 of 0.2 nM in cell-free assays, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively. Phase 3.

Chemical Information：

Molecular Weight (MW)		558.14
Formula		C28H36ClN5O3S
CAS No.		1032900-25-6
Solubility (25°C) *	DMSO	20 mg/mL warmed (35.83 mM)
	Water	Insoluble
	Alcohol	3 mg/mL (5.37 mM)

Biological Activity：

Targets IC50

Syk Monoamine trans Adenosine A3 re Adenosine trans 41 nM 2.74 μM 81 nM 1.84 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7917 mL	8.9583 mL	17.9167 mL
5 mM	0.3583 mL	1.7917 mL	3.5833 mL
10 mM	0.1792 mL	0.8958 mL	1.7917 mL
50 mM	0.0358 mL	0.1792 mL	0.3583 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last