Description：

Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.

Chemical Information：

Molecular Weight (MW)		482
Formula		C20H28ClN7O3S
CAS No.		1369761-01-2
Solubility (25°C) *	DMSO	43 mg/mL warmed (89.21 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

mTORC1 mTORC2 22 nM 65 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0747 mL	10.3734 mL	20.7469 mL
5 mM	0.4149 mL	2.0747 mL	4.1494 mL
10 mM	0.2075 mL	1.0373 mL	2.0747 mL
50 mM	0.0415 mL	0.2075 mL	0.4149 mL

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