Description：

Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM.

Chemical Information：

Molecular Weight (MW)		450.61
Formula		C29H38O4
CAS No.		34157-83-0
Solubility (25°C) *	DMSO	90 mg/mL (199.72 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Progesterone rec Glucocorticoid 0.2 nM 2.6 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2192 mL	11.0961 mL	22.1921 mL
5 mM	0.4438 mL	2.2192 mL	4.4384 mL
10 mM	0.2219 mL	1.1096 mL	2.2192 mL
50 mM	0.0444 mL	0.2219 mL	0.4438 mL

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