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Canertinib (CI-1033)

Canertinib (CI-1033)

Catalog Number: CC1175 Rank: comment rank 5

Size Price Qty
$ 118.00
$ 189.00
$ 468.00
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Description:

Canertinib (CI-1033) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3.

Chemical Information:

Molecular Weight (MW) 485.94
Formula

 

C24H25ClFN5O3

 

CAS No. 267243-28-7
Solubility (25°C) * DMSO 2 mg/mL (4.11 mM)
Water Insoluble
Alcohol 9 mg/mL (18.52 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0579 mL 10.2893 mL 20.5787 mL
5 mM 0.4116 mL 2.0579 mL 4.1157 mL
10 mM 0.2058 mL 1.0289 mL 2.0579 mL
50 mM 0.0412 mL 0.2058 mL 0.4116 mL


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