Description：

Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.

Chemical Information：

Molecular Weight (MW)		370.38
Formula		C19H19FN4O3
CAS No.		649735-46-6
Solubility (25°C) *	DMSO	74 mg/mL (199.79 mM)
	Water	Insoluble
	Alcohol	3 mg/mL (8.09 mM)

Biological Activity：

Targets IC50

STAT3 4.6 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6999 mL	13.4996 mL	26.9993 mL
5 mM	0.5400 mL	2.6999 mL	5.3999 mL
10 mM	0.2700 mL	1.3500 mL	2.6999 mL
50 mM	0.0540 mL	0.2700 mL	0.5400 mL

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