Description：

BMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM in a cell-free assay. It is 25-fold more selective for CDK1/2 than CDK4.

Chemical Information：

Molecular Weight (MW)		345.34
Formula		C18H17F2N3O2
CAS No.		582315-72-8
Solubility (25°C) *	DMSO	20 mg/mL (57.91 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Aβ 20 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.8957 mL	14.4785 mL	28.9570 mL
5 mM	0.5791 mL	2.8957 mL	5.7914 mL
10 mM	0.2896 mL	1.4478 mL	2.8957 mL
50 mM	0.0579 mL	0.2896 mL	0.5791 mL

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