Description：

BLU-554 is a potent, highly-selective, oral FGFR4 inhibitor with an IC50 value of 5 nM. The IC50s for FGFR1-3 is 624-2203 nM.

Chemical Information：

Molecular Weight (MW)		503.38
Formula		C24H24Cl2N4O4
CAS No.		1707289-21-1
Solubility (25°C) *	DMSO	100 mg/mL warmed (198.65 mM)
	Water	Insoluble
	Alcohol	2 mg/mL warmed (3.97 mM)

Biological Activity：

Targets IC50

EGFR 2 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9866 mL	9.9329 mL	19.8657 mL
5 mM	0.3973 mL	1.9866 mL	3.9731 mL
10 mM	0.1987 mL	0.9933 mL	1.9866 mL
50 mM	0.0397 mL	0.1987 mL	0.3973 mL

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