Description：

Bitopertin (RG1678,RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.

Chemical Information：

Molecular Weight (MW)		543.46
Formula		C21H20F7N3O4S
CAS No.		845614-11-1
Solubility (25°C) *	DMSO	100 mg/mL (184.0 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (184.0 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8401 mL	9.2003 mL	18.4006 mL
5 mM	0.3680 mL	1.8401 mL	3.6801 mL
10 mM	0.1840 mL	0.9200 mL	1.8401 mL
50 mM	0.0368 mL	0.1840 mL	0.3680 mL

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