Description：

BIO-acetoxime is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.

Chemical Information：

Molecular Weight (MW)		398.21
Formula		C18H12BrN3O3
CAS No.		667463-85-6
Solubility (25°C) *	DMSO	19 mg/mL warmed (47.71 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

PARP1 < 5 nM (Ki) [1

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5112 mL	12.5562 mL	25.1124 mL
5 mM	0.5022 mL	2.5112 mL	5.0225 mL
10 mM	0.2511 mL	1.2556 mL	2.5112 mL
50 mM	0.0502 mL	0.2511 mL	0.5022 mL

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