Description：

BIO is a specific inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/β in a cell-free assay, shows >16-fold selectivity over CDK5, also a pan-JAK inhibitor.

Chemical Information：

Molecular Weight (MW)		356.17
Formula		C16H10BrN3O2
CAS No.		667463-62-9
Solubility (25°C) *	DMSO	71 mg/mL (199.34 mM)
	Water	Insoluble
	Alcohol	6 mg/mL (16.84 mM)

Biological Activity：

Targets IC50

HDAC 7.5 to 16 nM [1

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.8076 mL	14.0382 mL	28.0765 mL
5 mM	0.5615 mL	2.8076 mL	5.6153 mL
10 mM	0.2808 mL	1.4038 mL	2.8076 mL
50 mM	0.0562 mL	0.2808 mL	0.5615 mL

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