Description：

BIIB021 is an orally available, fully synthetic small-molecule inhibitor of HSP90 with K_i and EC50 of 1.7 nM and 38 nM, respectively. Phase 2.

Chemical Information：

Molecular Weight (MW)		318.76
Formula		C14H15ClN6O
CAS No.		848695-25-0
Solubility (25°C) *	DMSO	64 mg/mL (200.77 mM)
	Water	Insoluble
	Alcohol	2 mg/mL (6.27 mM)

Biological Activity：

Targets IC50

JAK2 KIT FGFR1 Abl Aurora A  FLT3 0.15 μM 0.30 μM 36 nM 14 nM 48 nM 6.6 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1372 mL	15.6858 mL	31.3716 mL
5 mM	0.6274 mL	3.1372 mL	6.2743 mL
10 mM	0.3137 mL	1.5686 mL	3.1372 mL
50 mM	0.0627 mL	0.3137 mL	0.6274 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last