Description：

Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with K_i of 0.8 nM in a cell-free assay. Phase 2.

Chemical Information：

Molecular Weight (MW)		509
Formula		C24H33ClN4O6
CAS No.		273404-37-8
Solubility (25°C) *	DMSO	100 mg/mL warmed (196.46 mM)
	Water	Insoluble
	Alcohol	100 mg/mL warmed (196.46 mM)

Biological Activity：

Targets IC50

Aromatase 10 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9646 mL	9.8232 mL	19.6464 mL
5 mM	0.3929 mL	1.9646 mL	3.9293 mL
10 mM	0.1965 mL	0.9823 mL	1.9646 mL
50 mM	0.0393 mL	0.1965 mL	0.3929 mL

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