Description：

ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively; no inhibition observed against Mcl-1, Bcl-B or Bfl-1. Phase 2.

Chemical Information：

Molecular Weight (MW)		813.43
Formula		C42H45ClN6O5S2
CAS No.		852808-04-9
Solubility (25°C) *	DMSO	100 mg/mL (122.93 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

MEK 0.33 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.2294 mL	6.1468 mL	12.2936 mL
5 mM	0.2459 mL	1.2294 mL	2.4587 mL
10 mM	0.1229 mL	0.6147 mL	1.2294 mL
50 mM	0.0246 mL	0.1229 mL	0.2459 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last