Description：

(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM in cell-free assays, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.

Chemical Information：

Molecular Weight (MW)		292.33
Formula		C18H16N2O2
CAS No.		856925-71-8
Solubility (25°C) *	DMSO	58 mg/mL (198.4 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

CGRP 0.12 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.4208 mL	17.1040 mL	34.2079 mL
5 mM	0.6842 mL	3.4208 mL	6.8416 mL
10 mM	0.3421 mL	1.7104 mL	3.4208 mL
50 mM	0.0684 mL	0.3421 mL	0.6842 mL

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