Description：

XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, exhibiting >50-fold selectivity over JAK1, JAK3 and TYK2. Phase 1.

Chemical Information：

Molecular Weight (MW)		444.53
Formula		C25H28N6O2
CAS No.		945755-56-6
Solubility (25°C) *	DMSO	16 mg/mL (35.99 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2496 mL	11.2478 mL	22.4957 mL
5 mM	0.4499 mL	2.2496 mL	4.4991 mL
10 mM	0.2250 mL	1.1248 mL	2.2496 mL
50 mM	0.0450 mL	0.2250 mL	0.4499 mL

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