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Wortmannin

Wortmannin

Catalog Number: CC2914 Rank: comment rank 5

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Description:

Wortmannin is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. Also blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM in cell-free assays.

Chemical Information:

Molecular Weight (MW) 428.43
Formula

 

C23H24O8

 

CAS No. 19545-26-7
Solubility (25°C) * DMSO 85 mg/mL (198.39 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3341 mL 11.6705 mL 23.3410 mL
5 mM 0.4668 mL 2.3341 mL 4.6682 mL
10 mM 0.2334 mL 1.1671 mL 2.3341 mL
50 mM 0.0467 mL 0.2334 mL 0.4668 mL


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