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Description:
VU0357121 is a novel positive allosteric modulator (PAM) of mGlu5 with EC50 of 33 nM, is inactive or very weakly antagonizing at other mGlu receptor subtypes.
Chemical Information:
Molecular Weight (MW) 305.32 Formula
C17H17F2NO2
CAS No. 433967-28-3 Solubility (25°C) * DMSO 61 mg/mL (199.79 mM) Water Insoluble Alcohol 21 mg/mL (68.78 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.2753 mL 16.3763 mL 32.7525 mL 5 mM 0.6551 mL 3.2753 mL 6.5505 mL 10 mM 0.3275 mL 1.6376 mL 3.2753 mL 50 mM 0.0655 mL 0.3275 mL 0.6551 mL
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