Description：

Vistusertib (AZD2014) is a novel mTOR inhibitor with IC50 of 2.8 nM in a cell-free assay; highly selective against multiple PI3K isoforms (α/β/γ/δ). AZD2014 showed no or weak binding to the majority of kinases when tested at 1 μM.

Chemical Information：

Molecular Weight (MW)		462.54
Formula		C25H30N6O3
CAS No.		1009298-59-2
Solubility (25°C) *	DMSO	38 mg/mL (82.15 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1620 mL	10.8099 mL	21.6198 mL
5 mM	0.4324 mL	2.1620 mL	4.3240 mL
10 mM	0.2162 mL	1.0810 mL	2.1620 mL
50 mM	0.0432 mL	0.2162 mL	0.4324 mL

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