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Vismodegib (GDC-0449)

Vismodegib (GDC-0449)

Catalog Number: CC1238 Rank: comment rank 5

Size Price Qty
$ 118.00
$ 259.00
$ 679.00
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Description:

Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.

Chemical Information:

Molecular Weight (MW) 421.3
Formula

 

C19H14Cl2N2O3S

 

CAS No. 879085-55-9
Solubility (25°C) * DMSO 84 mg/mL (199.38 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3736 mL 11.8680 mL 23.7361 mL
5 mM 0.4747 mL 2.3736 mL 4.7472 mL
10 mM 0.2374 mL 1.1868 mL 2.3736 mL
50 mM 0.0475 mL 0.2374 mL 0.4747 mL


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