Description：

VE-821 is a potent and selective ATP competitive inhibitor of ATR with K_i/IC50 of 13 nM/26 nM in cell-free assays, shows inhibition of H2AX phosphorylation, minimal activity against PIKKs ATM, DNA-PK, mTOR and PI3Kγ.

Chemical Information：

Molecular Weight (MW)		368.41
Formula		C18H16N4O3S
CAS No.		1232410-49-9
Solubility (25°C) *	DMSO	74 mg/mL (200.86 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.7144 mL	13.5718 mL	27.1437 mL
5 mM	0.5429 mL	2.7144 mL	5.4287 mL
10 mM	0.2714 mL	1.3572 mL	2.7144 mL
50 mM	0.0543 mL	0.2714 mL	0.5429 mL

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