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Tofacitinib (CP-690550,Tasocitinib)

Tofacitinib (CP-690550,Tasocitinib)

Catalog Number: CC2945 Rank: comment rank 5

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Description:

Tofacitinib (CP-690550,Tasocitinib) is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1.

Chemical Information:

Molecular Weight (MW) 312.37
Formula

 

C16H20N6O

 

CAS No. 477600-75-2
Solubility (25°C) * DMSO 62 mg/mL warmed (198.48 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.2013 mL 16.0067 mL 32.0133 mL
5 mM 0.6403 mL 3.2013 mL 6.4027 mL
10 mM 0.3201 mL 1.6007 mL 3.2013 mL
50 mM 0.0640 mL 0.3201 mL 0.6403 mL


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