Description：

Thioguanine, a purine antimetabolite, inhibits DNMT1 activity through ubiquitin-targeted degradation, used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn\'s disease, rheumatoid arthritis) and organ transplant recipients.

Chemical Information：

Molecular Weight (MW)		167.19
Formula		C5H5N5S
CAS No.		154-42-7
Solubility (25°C) *	DMSO	17 mg/mL (101.68 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	5.9812 mL	29.9061 mL	59.8122 mL
5 mM	1.1962 mL	5.9812 mL	11.9624 mL
10 mM	0.5981 mL	2.9906 mL	5.9812 mL
50 mM	0.1196 mL	0.5981 mL	1.1962 mL

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