Description：

Abexinostat (PCI-24781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with K_i of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.

Chemical Information：

Molecular Weight (MW)		397.42
Formula		C21H23N3O5
CAS No.		783355-60-2
Solubility (25°C) *	DMSO	80 mg/mL (201.29 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

c-Kit VEGFR3 VEGFR1 PDGFR Ret VEGFR2 8 nM 6 nM 2 nM 84 nM 59 nM 3 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5162 mL	12.5811 mL	25.1623 mL
5 mM	0.5032 mL	2.5162 mL	5.0325 mL
10 mM	0.2516 mL	1.2581 mL	2.5162 mL
50 mM	0.0503 mL	0.2516 mL	0.5032 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last