Description：

Talazoparib (BMN 673) is a novel PARP inhibitor with IC50 of 0.58 nM in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. Phase 3.

Chemical Information：

Molecular Weight (MW)		380.35
Formula		C19H14F2N6O
CAS No.		1207456-01-6
Solubility (25°C) *	DMSO	38 mg/mL warmed (99.9 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6292 mL	13.1458 mL	26.2916 mL
5 mM	0.5258 mL	2.6292 mL	5.2583 mL
10 mM	0.2629 mL	1.3146 mL	2.6292 mL
50 mM	0.0526 mL	0.2629 mL	0.5258 mL

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