Description：

TAK-632 is a potent pan-Raf inhibitor with IC50 of 8.3 nM and 1.4 nM for B-Raf(wt) and C-Raf in cell-free assays, respectively, showing less or no inhibition against other tested kinases.

Chemical Information：

Molecular Weight (MW)		554.52
Formula		C27H18F4N4O3S
CAS No.		1228591-30-7
Solubility (25°C) *	DMSO	100 mg/mL(180.33 mM)
	Water	Insoluble
	Alcohol	2 mg/mL (3.6 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8034 mL	9.0168 mL	18.0336 mL
5 mM	0.3607 mL	1.8034 mL	3.6067 mL
10 mM	0.1803 mL	0.9017 mL	1.8034 mL
50 mM	0.0361 mL	0.1803 mL	0.3607 mL

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