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Description:
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.
Chemical Information:
Molecular Weight (MW) 254.24 Formula
C8H9N2O3S.H2O.Na
CAS No. 6209-17-2 Solubility (25°C) * DMSO 50 mg/mL warmed (196.66 mM) Water 50 mg/mL (196.66 mM) Alcohol 2 mg/mL warmed (7.86 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.9333 mL 19.6665 mL 39.3329 mL 5 mM 0.7867 mL 3.9333 mL 7.8666 mL 10 mM 0.3933 mL 1.9666 mL 3.9333 mL 50 mM 0.0787 mL 0.3933 mL 0.7867 mL
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