Description：

Sorafenib Tosylate is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM in cell-free assays, respectively.

Chemical Information：

Molecular Weight (MW)		637.03
Formula		C21H16ClF3N4O3.C7H8O3S
CAS No.		475207-59-1
Solubility (25°C) *	DMSO	127 mg/mL (199.36 mM)
	Water	0.01 mg/mL (0.01 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.5698 mL	7.8489 mL	15.6978 mL
5 mM	0.3140 mL	1.5698 mL	3.1396 mL
10 mM	0.1570 mL	0.7849 mL	1.5698 mL
50 mM	0.0314 mL	0.1570 mL	0.3140 mL

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